0.992 Was Not Replication: Why One Exciting Posterior Is Not a Causal Story
A T-cell signal reached PP4 near 0.992 in one dataset. Three independent public blood T-cell resources did not reproduce it.
#science
Posts tagged #science
Try to kill your target before you fund the next expensive step.
A fixed-scope, five-business-day adversarial review of one biological target or mechanism, ending in an ADVANCE, REWORK, STOP or NOT_EVALUABLE memo.
Biodius Target Challenge FAQ: Scope, Inputs, Price and Limits
What the Biodius Target Challenge reviews, what you send, what you get back, what it costs, and what it does not claim to do.
Not Evaluable Is a Result: When Public Human Genetics Cannot Decide the Causal Bridge
A plausible mechanism survived AI review. Public human genetics still could not decide the causal bridge, so the hypothesis was not promoted.
Falsification-First AI for Biological Target Assessment: What Four Prospective Experiments Taught Us About Scientific Agents
A technical report on four prospective experiments: why scientific AI is more useful when it preserves negative evidence and stops when data runs out.
